Metastatic cancer is difficult to treat and is associated with decreased survival rates in patients.  An important step in the progression of this disease is the migration of cancer cells throughout the body.   Researchers in the Losert lab at the University of Maryland’s Department of Physics study the dynamics of cell migration to better understand how to treat and diagnose metastatic disease.  Learn more about cell migration research in this article and join the BioHive on Thursday, Dec. 8 at 1 pm to ask Rachel any questions you may have about the physics of cancer cell migration, including:

1. How do healthy and cancer cells differ in their migration properties?  What differences do you see in the video below of migrating non-malignant and malignant cells?

2. How do we measure the migration behavior of different cell types?

3. Why is cell migration an interesting therapeutic target for cancer?

4. What can dynamic, physical measurements add to our options for patient diagnosis and the development of future cancer treatments?

Non-malignant M1 cells and malignant M4 cells show different migration behavior. The migration of these cells is discussed in Lee, et al. CSPO 2016